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Jama Pediatr

Initial brightening typically appears within 4-8 weeks of consistent treatment

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[DOI] [PMC free article] [PubMed] [Google Scholar] Bessone F

Li CH, Haider S, Shiah YJ, Thai K, Boutros PC

When a patient has a mutated gene, its blood contains excess amounts of a specific form of bilirubin (known as unconjugated bilirubin) because the patient does not produce enough quantity of the UGT enzyme, which is essential for the elimination of the bilirubin from the body