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Disruptions in iron metabolism lead to pathological conditions, with transferrin-Fe3+ complex formation occurring when transferrin binds external Fe3+ on the cell membrane, which is subsequently internalized by transferrin receptor 1 (24)
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Iron Dysregulation in Alzheimer's Disease: Multimodal Brain Permeable Iron Chelating Drugs, Possessing NeuroprotectiveNeurorescue and Amyloid Precursor ProteinProcessing Regulatory Activities as Therapeutic Agents. Progress in Neurobiology 82: 348360
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10.1016/j.expneurol.2021.113952 42 LoprinziP
Kopetz ES , Magnuson TH, Duncan MD, Bender JS, Lillemoe KD, Gordon TA, Cameron JL, Harmon JW
