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The patient has established cardiovascular disease with a documented history of at least one of the following: A) Previous myocardial infarction (MI) B) Previous stroke C) Symptomatic peripheral arterial disease (PAD), evidenced by one of the following: Intermittent claudication with an ankle-brachial index (ABI) less than 0.85 at rest Peripheral arterial revascularization procedure Amputation due to atherosclerotic disease D) Prior revascularization, such as coronary artery bypass grafting (CABG), percutaneous coronary intervention (PCI), or angioplasty, and

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SETD7 promotes TNF--induced proliferation and migration of airway smooth muscle cells in vitro through enhancing NF-B/CD38 signaling

However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing