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9.3 Cardiomyocyte protective In the angiotensin II-exposed H9C2 cells, ISA can increase the expression of Nrf2 and HO-1, enhancing the antioxidant capacity of cells, which helps to resist the detrimental effects imposed by angiotensin II, such as oxidative stress and apoptosis induction
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It was interestingly found that the phylum Cyanobacteria, which are photoautotrophic bacteria, possess a distinct -C3-hydroxylase, designated CrtR, which shows moderate homology not to CrtZ but to CrtW [189]
The A25-35 model caused cognitive deficits, hippocampal damage, reduced Bcl-2, increased Bax, lower antioxidant enzyme activity, and elevated ROS/MDA
