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En quienes tienen uremia puede generar debilidad muscular, y convulsiones en quienes padecen de trastornos convulsivos

Effects manifest gradually : Weeks 1-2 : better energy during workouts, less post-workout fatigue Weeks 2-4 : improved recovery, first signs on waist circumference Weeks 4-8 : measurable improvement in endurance and fat loss Weeks 8-12 : full effects on body composition and performance Muscle saturation takes several weeks, which is why long-term courses are important (8-12 weeks minimum)

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Protocols for CKRT and high-dose CKRT are included in Supplementary Information 3

Mosmann T (1983) Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays