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Academic Press, London, pp 121126 Aggarwal BB, Harikumar KB (2009) Potential therapeutic effects of curcumin, the anti-inflammatory agent, against neurodegenerative, cardiovascular, pulmonary, metabolic, autoimmune and neoplastic diseases

These signs often go hand in hand with underlying gut conditions that block proper cobalamin absorption

Additionally, a study found that neuronal release of D-serine modulates N-methyl-D-aspartate receptor (NMDAR) function, and some of the D-serine produced by neurons might be transported into astrocytes and metabolized via the peroxisomal D-amino acid oxidase (DAO) enzyme (Wolosker and Radzishevsky, 2013)

Increases energy levels, helping reduce fatigue throughout the day

For prevention of deficiency in vegans or vegetarians, The Vegan Society recommends either 10 micrograms daily or 2000 micrograms weekly

And thanks to the Buck Institute Gordon: Excellent