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These findings provided substantial evidence that c-Met has excellent potential as an effective agent for both the prevention and treatment of colorectal cancer

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On the basis of this association, Fine et al 88 proposed in 2000 that chronic hypoxia is the final common pathway that leads to the development of end-stage renal failure

U0126 alone altered neither c-MET phosphorylation nor HGF mRNA levels but counteracted the inhibitory effect of exogenous TGF-2 on p-c-MET and HGF mRNA in ZH-161 and ZH-305 (Fig