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Similarly, redox-responsive carriers incorporating disulfide bridges (cleaved by elevated glutathione in activated microglia or neurons) liberate bacosides or quercetin exactly at sites of neuroinflammation, amplifying Nrf2 activation and neuroprotection while remaining inert during circulation (180)

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Vitamin B12 deficiency supports pernicious anemia diagnosis and treatment as low B12 levels directly impair red blood cell production, guiding doctors to administer B12 supplementation as a primary and effective treatment strategy

doi: 10.3390/ijms22126453, 56
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The pathways converge on some downstream targets (such as mTOR) while also having distinct effects, possibly allowing for greater overall anabolic response than either pathway alone
