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Mycobacterium tuberculosis isocitrate lyases 1 and 2 are jointly required for in vivo growth and virulence

10.1016/j.pdpdt.2021.102215 18

This is a common concern for patients considering GLP-1 receptor agonists like semaglutide (Wegovy, Ozempic) and tirzepatide (Zepbound, Mounjaro)

The mixed Cluster 1 is composed of 83 genes (52 planktonic and 32 biofilm) (Supplementary Table 3)

AD4/NACA has been considered a prodrug for NAC since it is rapidly metabolized into NAC after AD4/NACA administration [141]

Erastin upregulated the expression of lncRNA GABPB1-AS1, inhibited the translation of GABPB1 and the expression of the peroxidase gene, leading to the accumulation of ROS and MDA, and promoting tumor cell death, suggesting that GABPB1-AS1 may be the key to Erastin-induced ferroptosis [136, 137] (Table 2)