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Dodson WL, Sachan DS, Krauss S, Hanna W

The process begins with endothelial dysfunction, mainly in medium- and large-sized arteries

In the setting of myocardial ischemia, the buildup of long-chain acyl-CoA within mitochondria interferes with ATP transport, thereby compromising cellular metabolism and viability (Furat et al

L., Silva, G

The included studies encompassed a variety of study designs, including randomized controlled trials (RCTs), observational studies, and systematic reviews

External calibration (30 to 1100 ng/mL L-carnitine and creatine) in conjunction with labeled internal standard addition (L-carnitine-(trimethyl-d9)-inner salt and creatine-(methyl-d3) monohydrate) was employed