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Many digestive disorders such as diarrhea, intestinal stress, and ulcerative colitis have been closely associated with alterations in butyric acid levels (Koh et al., 2016)

While one should avoid high doses of B vitamins, because high doses of certain vitamins can produce unwanted side effects, especially those that are fat-soluble, which the body holds in reserve

Thus, similar possible relationship between high amount hot chili pepper consumption and several peripheral pain inductions should be investigated by future studies

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doi: 10.1038/s41598-017-02268-0 103

collapsin response-mediated protein-2, CRMP-2)] (124)