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Here, we elucidate the chemical and genetic basis for anaerobic TMA generation from the L-carnitine-derived metabolite -butyrobetaine (bb) by the human gut bacterium Emergencia timonensis

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After determination of activity, R120, L121, W128, and T146 were chosen for further saturation mutation

N-Acetyl Cysteine (NAC) is a widely used compound known for its antioxidant, mucolytic, and cytoprotective properties

Outcome measures were the change in penile curvature (degrees), plaque size (volume or size), International Index of Erectile Function score, pain scores and change in penile length