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Clinically, older patients with dementia frequently show a cluster of behavioral disturbances, including learning disorders, amnesia, anxiety, and neuropathic pain 24

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Specific antibodies that inhibit tail binding not only obstruct substrate uptake and degradation in the lysosome (33), but also lead to a significant accumulation of autophagic vesicles in tissues (52)

By highlighting the interplay between mitochondrial function and disease, and by discussing the latest therapeutic modalities, this review aims to contribute to the advancement of mitochondrial medicine and the betterment of patient outcomes

Gatter M, Ottlik S, Kvesi Z, Bauer B, Matthus F, Barth G

doi: 10.7888/juoeh.40.157