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This buffering mechanism is particularly important for the oxidation of pyruvate and -ketoglutarate [60]

In addition, it has been reported that oxaliplatin treatment lowers the cytosolic pH of DRG neurons through binding to neuronal hemoglobin, which acts as a proton buffer

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The gRNA used was: TATTGTATCCCATGTGGAGTAGG

The use of a higher resolution might reduce this effect, but cannot prevent deletion of the signal of minor lipid species by dominating ions with similar m/z

A prominent result of CR or low mTORC1 signaling is a decrease in cancer incidence, which maybe related to the alterations in mTORC1-controlled metabolism 2,9