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A deeper understanding of the mechanisms of action of small molecules, the exact sites of action, the necessary dose to achieve the desired effect, and the optimal time to start antioxidant therapy for preventive or curative effects may provide a rational approach that may result in greater pharmacological and clinical success in low-molecular-weight antioxidant therapy

[DOI] [PMC free article] [PubMed] [Google Scholar] 14.Liu YL, Gordhandas S, Arora K, et al

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Food and Drug Administration (FDA) to treat APAP overdose ( This review starts with the general description and classification of DILI, further summarizes the underlying mechanisms of AILI, and highlights the current research and novel findings in the diagnosis, screening, and management of AILI

doi: 10.1016/j.jaci.2015.01.023 77 TonelliA

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