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Lastly, it is notable that the liquid medium routinely used for induction of gliotoxin biosynthesis (i.e., Czapek-Dox) provides a zinc-limiting culture condition ( gliZ expression and, hence, gliotoxin biosynthesis, whereas the function of GliZ would be dedicated to maintain steady expression levels of the gli genes and gliotoxin biosynthesis while zinc starvation persists
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Puerarin has wide pharmacological properties, especially the activation of Sirtuin-1 (Zhou et al., 2014
Kratz C, Lenard HG, Ruzicka T, Gartner J
& Baiocco, G
