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Furthermore, these haplotype associations require further analysis to exclude nearby HLA gene variantswhich may influence the observed immune phenotype due to linkage disequilibrium with specific C4 alleles (123)

Coadministration of vitamins B 12 and D during pregnancy have strong neuroprotective effects in Parkinson disease

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In some research contexts, periodic breaks may actually enhance outcomes by allowing receptor upregulation during rest periods, improving responsiveness when dosing resumes

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Clin Pharmacokinet 42:139151 [DOI] [PubMed] [Google Scholar] Grnroos M, Chen M, Jahnukainen T, Capitanio A, Aizman RI, Celsi G (2006) Methotrexate induces cell swelling and necrosis in renal tubular cells