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Glutathione activity in cells is critical for normal detoxification and defense mechanisms in every cell

LGSH derived from MGO is subsequently hydrolyzed by glyoxalase 2 (GLO2) to produce D-lactate and glutathione [33]

Hydroxyl radical is one of the most reactive radicals with a short lifetime, about 10 8 10 9 s

10.1016/j.tcb.2004.07.014 Trends Cell Biol

Previous studies in our lab have shown the accuracy of DEXA for body composition to be 3.8% as assessed by direct comparison with hydrodensitometry and scale weight

Additionally, in lung cancer, hyperactivation of Nrf2 enables cancer cells to regulate intracellular iron metabolism more effectively, thereby inhibiting iron-dependent lipid peroxidation and evading ferroptosis [10]