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Similar results were shown with a thiomaltol-based [Ru(II)]PF6 complex, which has been shown to induce apoptosis in breast cancer cells by inhibiting DNA topoisomerase II, with a particular affinity for the DNA-binding pocket of the enzyme [89]

P.BrockhoffA.BatramC.MenzelS.SonnabendC.BornS.et al (2010)

doi: 10.1016/0926-6917(93)90019-M 145 Bardag-GorceFLiJFrenchBAFrenchSW
