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Upregulation of Histone deacetylase 3 (HDAC3) in pulmonary fibrosis can lead to NRF2 inhibition, and by selectively inhibiting HDAC3 (e.g., using the drug RGFP966), the inhibitory effect on NRF2 can be reduced

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AMPK is involved in several pathways that induce ferroptosis, including AMPK-mTOR-SLC7A11, AMPK-BECN1-SLC7A11, and TIGAR-AMPK-SCD1 [103-105]

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