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Neurotox Res 14(4):343351 Zhou P, Qian L, Chou T, Iadecola C (2008) Neuroprotection by PGE2 receptor EP1 inhibition involves the PTEN/AKT pathway

Transl Psychiatry 2014

Giorgi C, Marchi S, Simoes ICM, Ren Z, Morciano G, Perrone M, et al

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In addition, astrocytes, which normally support neurons, become dysfunctional through a process called astrogliosis, which worsens glutamate imbalance and reduces neuronal support (Taylor et al., 2016), and genetic mutationssuch as SOD1 (causing harmful protein accumulation), FUS (interfering with RNA handling), and TBK1 or OPTN (which impair the cell's waste disposal system known as autophagy

In addition to increased shedding, thinning, dryness, and changes in texture, some dermatologic signs can signal low B12
