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Considering the substantial influence of physicochemical properties on the behavior of nanocomplexes in vitro and in vivo, we conducted a comprehensive investigation of various parameters including particle size, morphology, zeta potential, EE, LE, stability, and drug release behavior in the presence of the ROS and GSH

Conversely, cancer cells were less sensitive to inhibitors of cystine uptake (for example, erastin) and the thioredoxin pathway (for example, auranofin, aurothioglucose and PX-12) (Fig

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The scRNA-seq data showed that this pathway was highly increased in differentiating chondrocytes in the G6pdh chon growth plates (Extended Data Fig

CB2 antagonism leads to the displacement of MZ B cells into follicles when S1PR is absent and B cells can be positioned in the splenic MZ by simply up-regulating CB2 expression [39]