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They also bind to receptors in cells that regulate genetic function
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10.1152/japplphysiol.00885.2015 53
In the lack of demonstrative dermoscopic appearance, shave or punch biopsy is necessary to distinguish other malignities that are mentioned above histopathologically (20-22)
Additionally, similar to docetaxel, the activation of pro-survival pathways such as the mitogen-activated protein kinase (MAPK) pathway can contribute to resistance by promoting cell survival and proliferation (66)
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