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37 In one study of 13 kindreds with hereditary non-spherocytic hemolytic anemia and either single or no identified mutations in PKLR coding regions, whole genome sequencing identified five kindreds with unique PKLR deep intronic mutations predicted to perturb normal mRNA processing

Our work over the past decade showed that the proteins that cause cancer (oncogenes) are neuroprotective [9,10,11,12,13] to post-mitotic photoreceptor cells, whereas anti-oncogenes inhibit tumor progression and promote retinal degeneration [14,15,16]

doi: 10.1016/j.jddst.2020.102200 [DOI] [Google Scholar] 270.Yeh C-Y, Hsiao J-K, Wang Y-P, Lan C-H, Wu H-C

201,202 Activation of collagen synthesis Collagen, the most abundant protein in the body, becomes a crucial part of the ECM, and the biological adhesive that holds cells together