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[ 51 ] In a recent double-blind, placebo-controlled, crossover study, administration of pure anthocyanidins (80 mg daily) showed a small but statistically significant benefit in a group of patients with the related disorder of fibromyalgia

Animal studies show low acute toxicity, but human safety data remain limited,,

It also can result in common Hashimotos triggers, including food sensitivities (many with Hashimotos are sensitive to gluten, dairy, and/or soy) and less resistance to pathogenic invasions (which can further impact nutrient absorption, becoming a vicious cycle)

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Dark marks remain on the skin after inflammation heals

Patients should also try to limit foods with saturated fats and high cholesterol