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Quite a few feces metabolites that have protective effects on the brain were reduced in 8-week-old knockout mice

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In vitro studies involving HepG2 cells, PQQ enhances the expression of Sirt-1 and Sirt-3 at transcriptional and translational levels by targeting PGC-1, NRF-1/-2, and mitochondrial transcription factor A (MTFA)

2019;24:e78492

doi: 10.1038/srep05080
