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[DOI] [PMC free article] [PubMed] [Google Scholar] 75.Lucena-Cacace A, Umeda M, Navas LE, Carnero A

Its origin in gastric peptide research gives it a distinctive position in the peptide literature

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1) Pro-angiogenic signaling (VEGFR2 Akt eNOS) In cell and animal models, BPC-157 increases VEGFR2 expression/internalization and activates downstream Akt-eNOS signaling, supporting endothelial tube formation and blood-flow recovery after ischemia

[20] [21] In the dermal wounds of rabbits GHK-Cu facilitated wound healing, causing better wound contraction, faster development of granular tissue and improved angiogenesis