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NOMEs also have antiproliferative effects linked to nitroalkylation of RAD51 recombinase, a critical component in the DNA repair machinery

General systemic antioxidant therapy often fails to achieve the desired therapeutic effect, which emphasizes the importance of personalized and precision medicine

10.1034/j.1399-3054.1998.1030114.x Physiol

Treatment with either NR or the PARP inhibitor Olaparib resulted in improvements at the mitochondrial and proteostasis level

(2013) examined the possibility of a 5-HT 2C -GHSR1a heterodimer that explained the interaction between serotonin and ghrelin reported in the literature

Moreover, excessive MDA generation within cells is associated with major human diseases such as Alzheimer disease, cancer, cardiovascular disease, diabetes, and Parkinson disease [54]