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In models of ovarian and liver cancer, NRF2 signaling enhances resistance to inducers like erastin and sorafenib (97, 98), whereas its loss or inhibition increases sensitivity

Barcelona, SPAIN: OXFORD UNIV PRESS

We did shoot Dave going through the motions, but the light values and shifting light on him just didnt match. Cinesites team were supplied with 3D head scans and photographic reference of both actors in costume for the scene, says Jackson

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For others, it can be unsightly