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Human clinical studies have shown promising results, including a 12-year randomized controlled trial demonstrating improved cardiovascular outcomes and reduced mortality in elderly subjects with accelerated aging [4]

Age-Related Decline in Melatonin and Its MT1 Receptor Are Associated with Decreased Sensitivity to Melatonin and Enhanced Mammary Tumor Growth

Hayama, T

10.1371/journal.pone.0307735 277 YamamotoN.HasegawaK.MatsuzakiK.NaikiH.YanagisawaK

In experimental autoimmune encephalomyelitis (EAE) models, MCC950 effectively suppresses microglial activation and Th17 cell differentiation, consequently attenuating disease progression [384]

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