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In addition, a TNF- surge or a cytokine storm ( aroA mutant has been shown to paradoxically induce higher TNF- production than its unattenuated counterparts (125)

Phase I and Phase II detoxification pathways work together to process everything from environmental pollutants to metabolic byproducts

Li X, Zhao Y, Gong S, Song T, Ge J, Li J, et al

Clinical trial on edaravone demonstrated a significant reduction in the ALSFRSr score in ALS patients compared to placebo group [262,263]

(PubMed) Pennington JAT, Schoen SA, Salmon GD, Young B, Johnson RD, Marts RW

PubMed, Venn, Bernard J., et al
