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However, obesity and insulin resistance (IR) are presently acknowledged as significant causative factors in MetS

Low-dose naltrexone effects on plasma chemistries and clinical symptoms in autism: a double-blind, placebo-controlled study

Key mediators such as interleukin-6 (IL-6), IL-1, IL-8, and tumor necrosis factor- (TNF-) play pivotal roles in triggering the innate immune response, thereby promoting follicular hyperkeratosis and the characteristic inflammatory lesions of acne

The effects of environmental pollutants and exposures on hair follicle pathophysiology

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We summarize key mechanisms of action, categorize clinically relevant peptide classes, and address current limitations, including gaps in human data, safety considerations, and regulatory ambiguity