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10.5152/tjg.2018.17330 8 BannaiS.TsukedaH.OkumuraH

For most licensed drugs this form of toxicity is identified and characterised during preclinical studies in animals and monitored in clinical trials (Ch

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This approach ensures efficient payload release upon reaching the brain, demonstrating that targeted drug synergy holds promise for delivering high therapeutic efficacy and could serve as a foundation for future clinical applications [324]