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The other disorders included coronary vasospasm, aortic aneurysm dissection (three cases each), QT interval prolongation, cardiac arrest, development of symptoms of acute cardiomyopathy (two cases each), development of STEMI, coronary artery thrombosis, tachycardia associated with orthostatic reaction, and increased hypertension (one case each)

Increased pregnancy rate by about 50%

An improved understanding of the underlying mechanisms of action associated with these compounds will also facilitate the development of targeted treatment approaches

Sarchielli P, Mancini ML, Calabresi P