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10.1016/j.cca.2017.01.025 16 ChenS.ZhangZ.ZhangB.HuangQ.LiuY.QiuY.et al (2022)

In acidic conditions these carriers release their cargo, restore mitochondrial homeostasis, scavenge reactive oxygen species (ROS), and recalibrate cellular energy metabolism

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Whether this would be a proportional safety measure depends on the absolute prevalence of this interaction, which is currently not known

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c , Immunoblot of indicated proteins in the indicated HEK-293T SLC25A39 knockout cells expressing a vector control or SLC25A39 cDNA transduced with the indicated sgRNA