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10.1016/S0140-6736(12)62167-9 177
Int J Chronic Obstr Pulmonary Disease 2025:316373

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Khavinson VKh, Izmaylov DM, Obukhova LK, Malinin VV
Many MCAS patients have impaired pathways for converting glutamate into calming GABA, leading to "glutamate excitotoxicity"which can manifest as severe anxiety, insomnia, heart palpitations, and brain fog

The adrenal glands and the thyroid work in tandem to regulate stress responses and maintain hormonal balance