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We carefully examined the literature but were unable to find any studies that assessed the therapeutic potential of CGRP antagonists/blockers in preclinical or clinical COPD studies

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10.1007/s00424-015-1716-2 82 MouJ.PaillardF.TrumbullB.TrudeauJ.StokerM.KatzN

GPx-1 may, therefore, diminish proliferative and survival signaling activated in response to cytokines, growth factors, or vasoactive substances that activate ROS-generating NOXs (9)

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Structural variability among oligomers is substantial and plays a critical role in determining their toxic potential, as different conformational states can exert distinct effects on cellular homeostasis [51, 88, 158, 200, 223]