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Statistical analyses A descriptive analysis (mean, median and range) of the patients characteristics was performed for phase 1 and phase 2 of the DIVE-1 study

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Faecalibacterium prausnitzii increased 41% over placebo Anaerostipes increased 67% over placebo Both bacteria are butyrate producers and their benefits are associated with butyrate production (healthy microbiome, immunity, healthy inflammatory response, etc.) Tributyrin (as CoreBiome) Is the #1 selling SCFA on the market Has clinically substantiated bioavailability in the colon In a 48-hour study using a gastrointestinal model [and that was repeated in a four-week study], CoreBiome limited IL6, TNF-alpha and measurements of epithelial function through TEER (transepithelial electrical resistance), suggesting that it may support gut barrier function Is the ONLY SCFA with marketable claims Synergy with Larazotide, Guttides (BPC-157 + KPV): Critical component of GI protocols including Guttides (BPC-157 + KPV), Larazotide and low dose pentosan polysulfate

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[DOI] [PMC free article] [PubMed] [Google Scholar] 55

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