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In the body, bilirubin is excreted as waste, but bilirubin can serve as an antioxidant molecule, and the bilirubin-biliverdin redox couple has direct antioxidant function [80]

During the next 30 years, up to 22% of the world population will be older than 60 years (210)

Together, they bind to specific regions of DNA called antioxidant response elements (AREs), which are located in the promoter or enhancer regions of NRF2 target genes

Ad-p53 Gene Therapy for Lung Cancer, Best of ASCO, CD Rom, 2001

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Histone methylation and aging: lessons learned from model systems