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Cytoprotection via HO-1: Research suggests upregulation of heme oxygenase-1 (HO-1), reducing oxidative stress at the cellular level

Beyond cancer, PRODH dysfunction is also linked to neuropsychiatric and metabolic diseases, including schizophrenia 65,66 , and hyperprolinemia type I 67 , reflecting its broader role in regulating mitochondrial redox balance and prolineglutamate neurotransmitter metabolism

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Table 3 Tiered intervention strategies to mitigate the potential impact of ALAN on menstrual health