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Oral administration and lipid metabolism

E.MikamiK.NakanishiY.MatsuuraT.UtsunomiyaR.YanoH.et al (2022)

In sum, the successful achievement of oral bioavailability for peptides must overcome the pH challenges of the stomach, a host of attacking peptidases in the GI lumen and brush border, low epithelial permeability, as well as the liver first pass effect (Figure 1)

It requires medical supervision, proper dosing, and professional administration

The tube should be inverted to allow air bubbles to rise

My Dr was very upset and told me I needed the type with .9% alcohol and contacted my pharmacy to resend the vial already reconstituted