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At the same time, this also makes cancer cells more susceptible to irreversible oxidative damage and subsequent cell death (203, 204)

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A 2025 real-world safety comparison found the two drugs had distinct safety profiles, rather than one being safer overall

System x similar to those in the small intestine, that take up Cys from the plasma

doi: 10.1128/JB.182.19.5290-5299.2000 23 KuJ

By describing relationships between drug concentrations in accessible fluids like plasma and the subsequent pharmacological responses, pharmacokinetic analysis promotes enhancement of therapeutic efficacy while limiting drug toxicity