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Alterations in oxidative stress status during early alcohol withdrawal in alcoholic patients

Signaling pathways from Trk activation: PI3K/Akt pathway phosphorylates Bad (pro-apoptotic protein) preventing it from blocking Bcl-2 and Bcl-xL (anti-apoptotic proteins)

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2.8 ROS assays N2 worms synchronized to the L1 stage were transferred to NGM plates with or without drug (0.5 mM), approximately 50 per plate, and incubated at 20C for 2.5 days
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