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Long-term excessive use may pose potential colchicine-like risks, and systematic toxicology data are urgently needed to support its wider clinical application
But even after this first step, the development of cosmetic peptides progressed at a slow pace

10.1016/s0301-0082(99)00060-x 41 DuanJ.-Y.LinX.XuF.ShanS.-K.GuoB.LiF.-X.-Z.et al (2021)

The higher the melanin produced, the darker the skin gets

[Abstract]2021 Mar 19:545:195-202

These findings provided the basis for isolation of anti-ssDNA antibodies specific for a single strand of thymine nucleotides
