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Indeed, one U.S.-based cohort study with a median 12.5 year follow-up isolated a specific, significant mediatory effect of TMAO-related metabolites on red meat-associated development of atherosclerotic CVD (ASCVD) [69]
The ICR mice were housed in a vivarium, featuring a 12-h light cycle and a 21 C humidity- and temperature-controlled environment
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SdLDL particles are highly atherogenic due to their increased susceptibility to oxidation, prolonged circulation half-life, and enhanced propensity for arterial wall retention (99)
