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Long-term effects of metformin on diabetes prevention: identification of subgroups that benefited most in the diabetes prevention program and diabetes prevention program outcomes study
23 February 1879
doi:10.1007/s11064-023-04000-z
PGC-1 attenuates inflammation through suppression of NF-B signaling and NLRP3 inflammasome activation, linking mitochondrial function to inflammatory control [126,127,128]
However, since these data are derived from an animal model, it remains necessary to confirm these effects in humans before considering a clinical application
