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While the exact mechanisms remain unclear, two primary theories have been proposed: 1) an immune-mediated systemic reaction causing vasoconstriction and a prothrombotic state leading to ischemia and subsequent stroke

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The ATM specific kinase inhibitor KU60019 (Tocris, UK) was dissolved in DMSO to 100 mM then diluted to 5 M directly into media

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Goulas, A., Betzel, R

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It is important to note, however, that patients in the duloxetine group reported more moderate-intensity adverse effects (fatigue, somnolence, insomnia) compared to those in the placebo group, which resulted in a higher dropout rate (11% vs

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