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Crit Rev Food Sci Nutr 60(4):597625 Modi HR et al (2024) Mitochondria-targeted antioxidant therapeutics for traumatic brain injury

Blood 119:32633268

Recently, a new DON prodrug JHU395, has been developed to treat medulloblastoma (Pham et al., 2021)

Proenzyme activation is a more rapid method of increasing enzyme activity but, as a regulatory mechanism, it has the disadvantage of not being a reversible process

The detoxification function of GSTs As enzymes, GSTs are involved in many different detoxification reactions

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