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Archived from the original on 1 June 2023

Thus, structural and functional changes of these cells form a basis of the AHR in asthma [20,21]

Activation of these receptors enhances burst firing in dopaminergic neurons, increases dopamine release in the nucleus accumbens, thereby forming rewarding signals for external stimuli such as nicotine ( 5 , 3 , and 4 subtypes similarly play negative regulatory roles in nicotine uptake and aversive effects ( FIGURE 2 The rewarding mechanism of nicotine addiction is closely linked to the subtype-specific functions and molecular diversity of nicotinic acetylcholine receptors (nAChRs), the core of which lies in the spatiotemporal regulation of neurotransmitter release by distinct nAChR subtypes within the mesolimbic dopamine system

F.et al (2019)

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Shao HB, Chu LY, Lu ZH, Kang CM (2008) Primary antioxidant free radical scavenging and redox signalling pathways in higher plant cells