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However, this same GPR model also delivers the least accurate predictions for the 22 compounds of the external test set with an RMSEP of 0.59 and a MAE of 0.43, possibly indicative of overfitting to the training set data

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A broader 2024 review on cartilage engineering peptides highlighted AOD 9604 as a candidate that, in preclinical models, may support cartilage matrix restoration when delivered intra-articularly in OA settings